Synbiotic 365 is a combination of probiotics and prebiotics. It has a beneficial effect on the patient’s body by improving the survival and implantation of probiotic bacteria in the digestive tract by selectively stimulating the growth of these bacteria with a prebiotic.

Thus, the properties of synbiotic and its effect on health are associated with an individual combination of probiotic and prebiotic — currently, the most popular combination of bacteria of Bifidobacterium and Lactobacillus.

Synbiotic 365 has the following properties:

  • component safety for the patient;
  • proven benefits of synbiotic components for the patient;
  • selective stimulation of the growth of probiotic components on a prebiotic substrate;
  • increased probiotic survival when passing through the gastrointestinal tract;
  • stability of the structure during storage.

Due to the use of prebiotics, probiotic microorganisms obtain a higher tolerance to environmental conditions, including resistance to oxidation, low pH, and temperature. Stimulation of probiotics with prebiotics helps to regulate the metabolic activity in the intestine, the development of beneficial microbiota, and the inhibition of potential pathogens present in the digestive tract.

The use of synbiotics leads to a decrease in the concentration of undesirable metabolites, inactivation of nitrosamines and carcinogens, as well as a significant increase in the levels of short-chain fatty acids, ketones, carbon disulfides and methyl acetate, which can favorably affect the health of the patient.

The main effects that Synbiotic 365 have are:

  • increased number of Lactobacillus and Bifidobacterium and maintaining the balance of intestinal microbiota;
  • improvement in liver function in patients with cirrhosis;
  • immunomodulatory effects;
  • prevention of bacterial translocation and a decrease in the frequency of nosocomial infections in the postoperative period.

The randomized study of the use of a synbiotic containing 5 probiotics (Lactobacillus plantarum, Lactobacillus delbrueckii spp. Bulgaricus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium bifidum) and a significant reduction in liver function in patients with 6 patients had been observed in 6 patients over six months.

Synbiotic 365 contains the same 15 strains of probiotic bacteria, the effectiveness of which is confirmed in the studies described above.

One of the key properties of a synbiotic is resistance to adverse environmental conditions depends on the reliability of the capsule of the drug. The capsule protection technology allows the patient to protect the bacteria present in Synbiotic 365 from the acidic contents of gastric juice, bile salts, and digestive enzymes, and also makes it possible to store the drug at room temperature.

The balanced composition, the proven benefit, and safety of the components of Synbiotic 365, the stable structure and convenient frequency of administration (1 time per day), as well as the absence of lactose and casein in the composition (which makes it possible to use in patients with lactase deficiency), benefits Synbiotic 365 comparing with other medications, which are used as part of the correction of pathological changes in intestinal microflora of gastrointestinal tract during the treatment with a number of drugs (antibiotics, hormonal and non-steroidal anti-inflammatory drugs, antifungal agents) not only in adults but also in children.

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